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目的评估乳腺癌相关抗原(CA15-3)在原发性乳腺癌病人的术前预估中的价值.方法通过微粒子免疫分析法(MEIA)对518例乳腺癌病人的CA15－3血清水平进行研究.结果发现其水平与疾病分期、肿瘤大小、淋巴结状况、转移癌的出现和淋巴细胞渗入肿瘤密切相关,CA15－3的血清水平＞40U/ml对晚期癌症有85％的阳性预测值,其水平在各期乳腺癌的术后均有下降.结论在原发性乳腺癌的术前评估中应对CA15－3进行常规检测.“,”Objective To evaluate CAl5-3(breast carcinoma-associated antigen) in preoperative assessment of patients with primary breast carcinoma. Mathods We studied the serum level of CAl5-3 in 5l8 patients with breast carcinoma by ndcroparticle enzyme immunoassay(MEIA). Result We found CAl5-3 level had close correlation with the stage of disease, size of tumollr, status of lymph node, the presence of metastases and lymphocyte infltration. The serum level of CAl5-3>40U/ml had a positive predictive value of 85% for the presence of advanced disease. CA15-3 levels dropped post-operatively in all stages of the disease. Concusion We recornmend to use this valuabe tumollr marker as routine in the preoperative assessment of patienls with primary breast carcinoma.