镉(Cd)对哺乳动物具有生殖毒性,会对卵巢、睾丸和前列腺等生殖器官造成损伤[1-3]。近年来学术界发现了一种新型的环境内分泌干扰物,称为金属类雌激素或金属类激素,常见的有锑、Cd、钙、钴、铜、镍、铬、铅、汞和锡等[4]。这些金属类雌激素具有类雌激素作用,被发现与雌激素相关疾病如乳腺癌、子宫内膜移位、子宫肌瘤和子宫内膜癌等的发生有密切关系[5]。随着对环境内分泌干扰物研究的不断深入,Cd Cadmium (Cd) has reproductive toxicity to mammals and can cause damage to reproductive organs such as ovaries, testicles and prostate glands [1-3]. In recent years, academia has discovered a new type of environmental endocrine disruptors called metal estrogens or metal hormones, such as antimony, cadmium, calcium, cobalt, copper, nickel, chromium, lead, mercury and tin 4]. These metaloid estrogens have estrogen-like effects and are found to be closely linked to estrogen-related diseases such as breast cancer, endometrial translocation, uterine fibroids, and endometrial cancer [5]. With the constant research on environmental endocrine disruptors, Cd