目的对比分析血清与血浆标本中常规生化项目检测结果的差异。方法选取我院120例健康体检者随机分为对照组和实验组各60例,对照组采用普通血清标本,实验组采用肝素钠抗凝血浆,分别进行20项常规生化指标检测,比较两组检查结果。结果实验组Ca~(2+)、TP、ALT、AST结果明显低于对照组,而Glu、TBili结果显著高于对照组,差异具有统计学意义(P<0.05)。结论血清、血浆标本中部分生化项目检测存在较大的差异,因此,临床上应根据实际测定项目选择合适的检验标本,以保证检测的准确性。 Objective To comparatively analyze the differences of the test results of routine biochemical items in serum and plasma samples. Methods 120 healthy subjects in our hospital were randomly divided into control group and experimental group of 60 cases, the control group using ordinary serum samples, the experimental group using heparin sodium anticoagulated plasma, respectively, 20 routine biochemical tests, compared two groups of tests result. Results The results of Ca ~ (2 +), TP, ALT and AST in the experimental group were significantly lower than those in the control group, while the results of Glu and TBili in the experimental group were significantly higher than those in the control group (P <0.05). Conclusion There are big differences in some biochemical items in serum and plasma samples. Therefore, in clinical practice, appropriate test samples should be selected according to the actual measurement items to ensure the accuracy of the test.