33%硫酸镁溶液是医院常用的容积性泻药,又称盐类泻药。按常规配制的溶液在室温下放置常可出现黄色或棕色沉淀。我们在原配方中加入少量稀盐酸,配制后的溶液经过流通蒸气灭菌30分钟后应用。改进后的溶液,室温放置180天无黄色或棕色沉淀生成,无细菌生长,质量稳定,符合中国药典质控要求。 33% magnesium sulfate solution is commonly used in hospitals volume laxatives, also known as salt laxatives. Conventional solution prepared at room temperature can often appear yellow or brown precipitate. We add a small amount of dilute hydrochloric acid in the original formula, after the preparation of the solution through steam sterilization after 30 minutes. The improved solution, placed at room temperature for 180 days without yellow or brown precipitate generated, no bacterial growth, stable quality, in line with the Chinese Pharmacopoeia quality control requirements.