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Two mild-cytotoxic bistetrahydrofuran (THF) ring annonaceous acetogenins named calamistrins F (1) and G (2) were isolated from the ethanolic extract of the roots of U .calamistrata Hance. Their structures including the relative and absolute configurations were determined by chemical derivation and spectral analysis. Calamistrins F and G were a pair of epimers at C-26 which both had THF ring from C-18 to C-25 and three OH groups at C-5, C-17 and C-26.
Two mild-cytotoxic bistetrahydrofuran (THF) rings annonaceous acetogenins named calamistrins F (1) and G (2) were isolated from the ethanolic extract of the roots of U. calamistrata Hance. Their structures including the relative and absolute configurations were determined by chemical derivation and spectral analysis. Calamistrins F and G were a pair of epimers at C-26 which both had THF ring from C-18 to C-25 and three OH groups at C-5, C-17 and C-26.