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氟脲嘧啶(Fluorouraci lum,5—Fu)为嘧啶类抗代谢药,能抑制细胞内胸腺嘧啶脱氧核苷的生成,阻碍DNA生物合成,引起细胞损伤。临床主要用于消化道癌如胃癌、结肠癌、直肠癌、肝癌、乳腺癌、卵巢癌、宫颈癌、恶性葡萄胎、绒毛膜上皮癌及膀胱癌等的治疗。近年来,在治疗常见疾病的临床应用日益广泛,并获得较好的疗效,本文对此做一简要概述。 1 急性胰腺炎 急性胰腺炎是胰腺消化酶对自身引起的急性化
Fluorouracil luminol (5-Fu) is a pyrimidine antimetabolite which can inhibit the generation of thymidine in cells, hinder DNA biosynthesis and cause cell damage. Clinical mainly for the digestive tract cancer such as stomach cancer, colon cancer, rectal cancer, liver cancer, breast cancer, ovarian cancer, cervical cancer, malignant mole, choriocarcinoma and bladder cancer treatment. In recent years, the clinical application of common diseases in the treatment of an increasingly wide range, and get better curative effect, this article to do a brief overview. Acute pancreatitis Acute pancreatitis is caused by pancreatic digestive enzymes on their own