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目的:分析中药注射剂的不良反应,并探讨预防措施,为临床合理用药提供参考。方法:对中药注射剂不良反应65例进行回顾性分析,观察不良反应累及的器官和系统,探讨年龄、性别、给药速度、药物联用等因素的影响。结果:中药注射剂不良反应以过敏反应为主,主要累及皮肤及附件,与高龄或低龄、给药速度过快、药物联用等因素有关,与性别无关。临床应用时应注意详细询问过敏史、控制给药速度、单一用药等预防措施。结论:完善生产工艺,坚持辨证施治,使用前进行过敏试验,注意监测不良反应,避免诱发因素,做到临床用药安全有效。
Objective: To analyze the adverse reactions of traditional Chinese medicine injections and to explore preventive measures to provide reference for rational clinical use. Methods: 65 cases of adverse reactions of Chinese medicine injection were retrospectively analyzed. The organs and systems involved in adverse reactions were observed. The effects of age, sex, drug delivery rate and drug combination were also investigated. Results: The adverse reactions of Chinese traditional medicine injections were mainly anaphylactoid reaction, which mainly involved the skin and appendages, which were related to the older or younger age, the fast delivery rate, drug combination and other factors, and had nothing to do with gender. Clinical application should pay attention to detailed history of allergy, control the drug delivery rate, a single medication and other preventive measures. Conclusion: Improve the production process, adhere to the syndrome differentiation, allergy test before use, pay attention to monitoring adverse reactions, to avoid predisposing factors, so that clinical drug use is safe and effective.