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抗体形成在衰老过程发生上可能起到重要作用.新近的研究肯定了DNA改变在抗体形成过程中的作用.那么,在抗体形成过程中,特异差错的蓄积是不是衰老的开始呢?本文综述的新证据表明,DNA修复(DNA改变的一个途径)可能与抗体形成具有某些共同的途径.目前,DNA修复研究引出了某些与抗体形成有关的概念,如:诱导机能、信号、诱导反应的不均一性,一些核苷酸顺序的易变性,修复的调节和识别特异性.随着对特异抗体形成途径及其调节机理的深入研究,我们注意到特异的DNA改变步骤,它有可能是衰老的早期阶段.本文
Antibody formation may play an important role in the aging process. Recent studies have confirmed the role of DNA changes in antibody formation. So, in the process of antibody formation, the accumulation of specific errors is not the beginning of aging? New evidence suggests that DNA repair (a pathway for DNA changes) may have some common pathways with antibody formation. At present, DNA repair studies have led to certain concepts related to antibody formation, such as: induction, signaling, and inducible responses. Heterogeneity, variability of some nucleotide sequences, the regulation of repair, and recognition specificity. With the in-depth study of specific antibody-forming pathways and their regulatory mechanisms, we have noted specific DNA alteration steps, which may be senescence. The early stage of this article.