论文部分内容阅读
本文用化学比色法测定了２２例细菌性角膜溃疡患者和３０例正常人泪液及血清超氧化歧化酶（ＳＯＤ）活力。结果表明病组与对照组泪液ＳＯＤ活力分别为１１．２３±０．８７ｕｇ／Ｌ和４２．１１±０．９２ｕｇ／Ｌ，两者差异非常显著（Ｐ＜０．０１），血清ＳＯＤ活力分别为２５９．９４±２．２３ｕｇ／Ｌ和２６８．４４±２．０２ｕｇ／Ｌ，两者差异不显著（Ｐ＞０．０５）。认为，细菌性角膜溃疡时局部存在自ＶＹＵ由基氧化损伤作用，在进行有效的抗菌治疗的同时，局部应用ＳＯＤ抗氧化治疗，对于减轻角膜组织损害是必要的。
In this paper, 22 cases of bacterial corneal ulcer patients and 30 normal people were measured by chemical colorimetry tear and serum superoxide dismutase (SOD) activity. The results showed that the activity of SOD in the tear fluid of the disease group and the control group were 11.23 ± 0.87ug / L and 42.11 ± 0.92ug / L, respectively, with significant difference (P <0.01). The activity of SOD in the serum was 259.94 ± 2.23ug / L and 268.44 ± 2.02ug / L respectively, with no significant difference (P> 0.05). It is considered that bacterial corneal ulcer exists locally from the oxidative damage of VYU, and in the course of effective antibacterial treatment, the local application of SOD antioxidant therapy is necessary for alleviating corneal tissue damage.