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目的:了解我院临床去甲万古霉素的使用情况,评价用药合理性,为临床合理应用延长其使用寿命提供客观的参考依据。方法:使用PASS软件,对我院2007年1月～2008年2月住院患者中使用去甲万古霉素的127份病历进行分析。结果:在127份病例中,有63例做了细菌培养,阳性率为58.73%;用药时间基本合理;用药前后的肾功能亦无显著变化。结论:目前去甲万古霉素类药品的临床应用有所放宽,不合理用药也随之增加。应采取措施,严格掌握适应证,限制预防用药,保护该类药物的使用寿命。
Objective: To understand the clinical use of norvancomycin in our hospital, to evaluate the rationality of the drug and to provide an objective reference for extending the service life of the clinical rational use. METHODS: PASS software was used to analyze 127 medical records of norvancomycin in hospitalized patients from January 2007 to February 2008 in our hospital. Results: Of the 127 cases, 63 cases had bacterial culture, the positive rate was 58.73%. The treatment time was reasonable and the renal function before and after treatment did not change significantly. Conclusion: At present, the clinical application of norvancomycin has been relaxed and irrational use of drugs has also increased. Measures should be taken to strictly control the indications, to limit the prevention of medication, to protect the life of such drugs.