养正合剂的免疫调节作用

来源 :中国药科大学学报 | 被引量 : 0次 | 上传用户:ustczhy
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实验表明养正合剂15,30g/kg(ig)显著升高正常及环磷酰胺免疫抑制小鼠碳粒廓清速率,增强正常及强的松龙所致免疫低下小鼠迟发型超敏反应;30g/kg升高环磷酰胺免疫抑制小鼠的溶血素含量,并促进ConA诱导的大鼠脾细胞产生IL-2,但对正常小鼠血清溶血素含量、腹腔巨噬细胞吞噬功能及NK细胞的杀伤能力均无显著影响。提示养正合剂对机体低下的免疫功能具有调节活性。 Experiments showed that Yangzheng Mixture 15, 30g/kg (ig) significantly increased the rate of carbon clearance in normal and cyclophosphamide immunosuppressed mice, and enhanced the delayed type hypersensitivity reaction in normal and prednisolone-induced immunocompromised mice; 30g /kg Increases the hemolysin content of cyclophosphamide immunosuppressive mice and promotes the production of IL-2 by ConA-induced rat spleen cells, but the serum hemolysin level, phagocytosis of peritoneal macrophages, and NK cells in normal mice No significant effect on killing capacity. It is suggested that Yangzheng mixture has regulating activity on the body’s low immune function.
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