论文部分内容阅读
目的研究舒芬太尼联合罗哌卡因用于分娩镇痛时对母婴的影响。方法选择无相关药物禁忌证、自然分娩的初产妇随机等分为A、B两组,共160例,A组给予舒芬太尼0.3μg/ml 0.1%+罗哌卡因,B组给予芬太尼2μg/ml 0.1%+罗哌卡因,另选对照组(C组80例)无镇痛药物的初产妇。结果 A组与B组比较,给药后10 min,断药1 h后疼痛明显减轻,VAS评分下降明显(P<0.05),两组均无明显运动阻滞;C组较A、B两组产程二明显延长,产程一明显短;三组产妇产钳术,剖宫术率差异无统计学意义(P>0.05),在缩宫素的使用率方面,A、B两组较C组高(P<0.05);三组新生儿在Apgar评分方面差异无统计学意义(P>0.05),A、B两组个别产妇出现皮肤瘙痒、恶心呕吐,但差异无统计学意义。结论舒芬太尼联合罗哌卡因用于分娩镇痛起效快,维持时间长,第二产程时间延长,第一产程时间缩短,缩宫素使用率升高而剖宫术率和产钳率不受影响。
Objective To study the effect of sufentanil combined with ropivacaine on maternal and infant during labor analgesia. Method selection No relevant drug contraindications, spontaneous delivery of primipara was randomly divided into A, B two groups, a total of 160 cases, A group given sufentanil 0.3μg / ml 0.1% + ropivacaine, B group was given Fen Taiji 2μg / ml 0.1% + ropivacaine, alternative control group (C group 80 cases) no primipara. Results Compared with group B, the pain decreased significantly and the VAS score decreased significantly (P <0.05) at 10 min after drug administration in group A, but there was no significant block in both groups. Compared with group A and group B (P> 0.05). There was no significant difference in the rate of cesarean section between the three groups (P> 0.05). In the aspect of oxytocin utilization, A and B groups were significantly higher than C group P <0.05). There was no significant difference in Apgar score between the three groups (P> 0.05). The pruritus, nausea and vomiting of some maternal women in groups A and B were not statistically significant. Conclusion Sufentanil combined with ropivacaine is effective in labor analgesia for onset of fasting, long-term maintenance, prolonged second stage of labor, shortening of the first stage of labor and high rate of oxytocin. However, the rates of cesarean section and forceps Not affected.