Ⅰ型糖尿病是一种与HLA-Ⅱ类抗原密切相关的疾病,各民族特异的单倍型分布导致了种族间不同的与IDDM的相关格局。这种相关性是由于HJA-Ⅱ类抗原作为一个重要角色参与并影响了IDDM的发生,尤其是Ⅱ生类抗原中的DQ更为重要,其α链及β链均参与此作用。 Type 1 diabetes is a disease closely related to HLA class II antigens, and ethnic-specific haplotype distributions lead to inter-ethnic differences associated with IDDM. This correlation is due to HJA-Ⅱ antigen as an important role in the participation and affect the occurrence of IDDM, especially in the second class of antigen EQ DQ is more important, the α-chain and β-chain are involved in this role.