论文部分内容阅读
目的分析新生儿缺氧缺血性脑病血清电解质变化及临床意义。方法选择本院诊断为HIE的患儿70例和同期50例正常新生儿为研究对象,测定静脉血清电解质值,进行比较分析。结果HIE组与对照组电解质比较,Na+、CL-、Ca2+明显降低,差异有统计学意义(Na+、CL-、Ca2+P<0.05),K+差异无统计学意义(P>0.05)。不同程度HIE组电解质,HIE程度与Na+、CL-、Ca2+降低有明显的正相关系(P<0.05),而K+差异无统计学意义(P>0.05)。结论新生儿HIE极易合并水电解质紊乱,出现低钠、低氯、低钙血症,并且与HIE的严重程度呈正相关,及时检测电解质,有助于分析病情及评价病情严重程度,指导临床治疗。
Objective To analyze the changes of serum electrolytes in neonates with hypoxic-ischemic encephalopathy and its clinical significance. Methods Seventy patients with HIE diagnosed in our hospital and 50 normal neonates during the same period were enrolled in this study. The values of serum electrolytes were measured and compared. Results Compared with the control group, the levels of Na +, CL- and Ca2 + in the HIE group were significantly decreased (P <0.05). There was no significant difference between the two groups (P <0.05). There was a significant positive correlation between the level of HIE and the levels of Na +, CL- and Ca2 + in HIE group (P <0.05), but there was no significant difference in K + between the two groups (P> 0.05). Conclusion Neonatal HIE easily combined with water and electrolyte disorders, hyponatremia, hypochlorine, hypocalcemia, and the severity of HIE was positively correlated to the timely detection of electrolyte, help to analyze the disease and evaluate the severity of the disease, and guide clinical treatment .