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目的分析在冠心病患者诊断中进行胱抑素C检测的效果。方法随机选择2014年1月至2017年4月在本院接受治疗的冠心病患者120例参与研究,根据疾病类型分为稳定型心绞痛(SA)组、急性心肌梗死(AMI)组、不稳定型心绞痛(UA)组,另外选择40例同期非冠心病患者作为对照组,各组均进行胱抑素C检测,分析检测结果。结果稳定型心绞痛(SA)组的胱抑素C水平检测结果为(1.14±0.28)mg/L,急性心肌梗死(AMI)组为(1.10±0.38)mg/L,不稳定型心绞痛(UA)组为(1.48±0.51)mg/L,对照组为(1.03±0.31)mg/L。高密度脂蛋白胆固醇、高血压病史、年龄、性别、胱抑素C水平都是冠状动脉病变的危险因素。结论胱抑素C水平高低和冠状动脉病变程度具有相关性,通过检测胱抑素C水平能够帮助了解冠心病患者的病变程度,从而为临床治疗方案的制订提供科学指导。
Objective To analyze the effect of cystatin C in the diagnosis of coronary heart disease. Methods A total of 120 CHD patients treated in our hospital from January 2014 to April 2017 were randomly divided into stable angina (SA) group, acute myocardial infarction (AMI) group, unstable type Angina pectoris (UA) group, another 40 patients with non-coronary heart disease in the same period were selected as control group. Cystatin C was detected in all groups and the test results were analyzed. Results The serum levels of cystatin C in patients with stable angina pectoris (SA) were (1.14 ± 0.28) mg / L and those in AMI patients were (1.10 ± 0.38) mg / L and those with unstable angina pectoris (UA) (1.48 ± 0.51) mg / L in the control group and (1.03 ± 0.31) mg / L in the control group. High-density lipoprotein cholesterol, history of hypertension, age, gender, and cystatin C levels are all risk factors for coronary artery disease. Conclusion The level of cystatin C is correlated with the severity of coronary artery disease. The detection of cystatin C can help to understand the degree of coronary artery disease and provide scientific guidance for the development of clinical treatment plan.