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为了探讨不同治疗方法及组织学类型对皮肤恶性肿瘤治疗效果的影响。对我院1977年到1992年治疗的可供分析的72例皮肤及附件恶性肿瘤就治疗方法,组织学类型,照射总剂量及分割剂量,照射野大小等与5年,10年生存病例数及生存率的关系进行分析研究。结果表明:皮肤恶性肿瘤总的放射治疗失败率为26.4%(19/72),14例基底细胞癌采用单次剂量3.0~3.5Gy组5年,10年生存率分别为78.5%。70.0%;常规剂量组5年,10年生存率分别为79.8%,62.9%。在49例基底细胞癌中,5年,10年生存率综合治疗组为86.4%,50%,单纯放疗组为85.2%,48.0%;照射野超过肿瘤边缘大于2cm组分别为69.2%,40.4%;超边小于2cm组为88.0%,29.2%。基底细胞癌生存率较其他肿瘤高,单次剂量以3.0~4.0Gy治疗效果较好,综合治疗组与单纯放疗组以及照射野超过肿瘤边缘大于2cm组和超边小于2cm组5年,10年生存率经统计学处理,无显著性差异。基底细胞癌放疗照射总剂量以51~60Gv最佳。
In order to explore the different treatment methods and histological types of skin cancer treatment effect. In our hospital from 1977 to 1992 for the treatment of 72 cases of skin and appendix malignant tumors on the treatment methods, histological types, total exposure dose and split dose, the size of the radiation field and 5 years, 10 cases of survival and Survival rate of the relationship analysis. The results showed that the total radiotherapy failure rate was 26.4% (19/72) in skin malignant tumors and 5 years in 14 basal cell carcinomas with single dose 3.0-3.5 Gy, the 10-year survival rates were 78 .5%. 70.0%. The 5-year and 10-year survival rates of conventional dose group were 79.8% and 62.9% respectively. In 49 cases of basal cell carcinoma, the 5-year and 10-year survival rates were 86.4% and 50% in the comprehensive treatment group and 85.2% and 48.0% in the radiotherapy alone group, respectively Which was 69.2% and 40.4% respectively; 88.0% and 29.2% in the ultramarine less than 2cm group. Basal cell carcinoma survival rate higher than other tumors, single dose 3.0 ~ 4.0Gy better treatment effect, comprehensive treatment group and radiotherapy group and the radiation field more than tumor edge more than 2cm group and ultra-edge less than 2cm group for 5 years The 10-year survival rate was statistically significant, with no significant difference. Basal cell carcinoma radiotherapy irradiation with a total dose of 51 ~ 60Gv best.