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目的 :探讨男、女不育与解脲脲原体 ( Ureaplasma U realyticum,UU )感染的关系 ,进一步研究 UU感染致男性不育的机制。方法 :应用分离培养法对 3 3 6对夫妇 ( 772例 )不育患者 (不育组 )及 12 4例正常生育者 (对照组 )进行生殖道解脲脲原体 ( UU)检测 ,并对不育组男性精液进行常规分析。结果 :不育组和对照组 UU检出率分别为 5 8.8%、 12 .1% ,不育组 U U检出率明显高于对照组 ( P <0 .0 1) ,不育组中受 UU感染的男性精子质量低于未受感染组 ( P <0 .0 5 )。结论 :生殖道解脲脲原体感染可能是导致男、女不育的原因 ,其机制之一可能是 UU导致男性精子质量降低
Objective: To investigate the relationship between male and female infertility and Ureaplasma Urealyticum (UU) infection and further investigate the mechanism of male infertility caused by UU infection. Methods: Urogenital Ureaplasma urealyticum (UU) was detected in 3 326 male infertile patients (infertile group) and 12 4 normal fertile subjects (control group) by isolation and culture method. Male infertile semen routine analysis. Results: The detection rates of UU in infertility group and control group were 58.8% and 12.1% respectively. The detection rate of UU in infertility group was significantly higher than that in control group (P <0.01) The quality of infected male sperm was lower than that of the uninfected group (P <0.05). CONCLUSIONS: Urogenital infection of the genital tract may be the cause of male and female infertility, and one of the mechanisms may be the reduction of male sperm quality due to UU