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目的研究增殖细胞核抗原ki-67对宫颈病变的分流作用。方法所有宫颈ASC-US病例均行薄层液基涂片检测,同时行Ki-67免疫组化染色,以病理活检作为诊断为标准,预测Ki-67对宫颈病变ASC-US的鉴别意义。结果 A组:9.09±3.11;B组:17.96±4.49;C组:65.43±15.42;F值156.18;P<0.05,经比较3组间差异有统计学意义。结论 Ki-67免疫组化染色对ASC-US的分流具有重要参考价值,值得临床推广用用,是较为理想的筛查方法。
Objective To study the shunt effect of proliferating cell nuclear antigen ki-67 on cervical lesions. Methods All cervical ASC-US cases were examined by thin-section liquid-based smears and Ki-67 immunohistochemical staining. Pathological biopsy was used as the diagnostic criteria to predict the differential significance of Ki-67 in cervical lesions ASC-US. Results A group: 9.09 ± 3.11; B group: 17.96 ± 4.49; C group: 65.43 ± 15.42; F value 156.18; P <0.05, after comparing the three groups was statistically significant. Conclusion The immunohistochemical staining of Ki-67 has an important reference value for the shunting of ASC-US, which is worthy of clinical application. It is an ideal screening method.