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对于恒河猴的正常性腺机能需要脉冲性的分泌LH,这又取决于下丘脑脉冲性地释放LH-RH。用灌流泵脉冲性地长期注入LH-RH能引致下丘脑损伤猴和新生猴排卵,并能在非繁殖季节的公羊和延迟发育的男孩引致睾丸的机能活动。但是,持续脉冲性给药的方法要求加强对病人的观察,不如每天注射适量LH-RH或其类似物方便实用。因此,本文在非繁殖季节的雄猴进一步比较了脉冲性补充LH-RH与间断性给予低剂量LH-RH高活性类似
The normal gonadal function of rhesus needs a burst of LH secretion, which in turn depends on the hypothalamus to release LH-RH pulsedly. Long-term pulsatile infusion of LH-RH with a perfusion pump results in the ovulation of the monkey and the newborn monkey with hypothalamic lesions and leads to testicular functional activity in ram and late-developing boys in non-breeding seasons. However, the continuous pulse of the method requires strengthening the patient’s observation, it is better daily injection of LH-RH or its analogues convenient and practical. Therefore, in this paper, non-breeding season males further compared the pulse of LH-RH supplementation with intermittent low-dose LH-RH high activity similar