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人星状病毒 (HAstV)是RNA病毒的新家族 ,从我国河南和北京两地区的急性腹泻患儿便样中鉴定了 7株星状病毒 ,经电镜观察病毒颗粒直径约为 2 8nm ,表面呈五角或六角星状形态 ,用RT PCR检定为阳性 ,比较PCR扩增产物的核苷酸序列构建的序列同源性树表明 ,1 990年在河南流行的星状病毒主要为HAstV 1 ,另有一株HAstV 5,1 996年北京流行株为HAstV 5。对HAstV患儿的临床症状进行了讨论。以上结果为我国病毒性胃肠炎流行的预防提供科学根据
Human astrovirus (HAstV) is a new family of RNA viruses. Seven astroviruses were identified from the samples of children with acute diarrhea in Henan and Beijing in China. The diameter of the virus particles was about 28 nm, Pentagonal or hexagonal star-like morphology, positive by RT PCR test. Comparing the nucleotide sequence of the PCR amplification products to construct the sequence homology tree showed that the astrovirus circulating in Henan in 1990 was mainly HAstV 1, and another Strain HAstV 5, 1996 Beijing epidemic strain HAstV 5. The clinical symptoms of children with HAstV were discussed. The above results provide a scientific basis for the prevention of viral gastroenteritis in our country