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目的 观察~(131)碘(~(131)Ⅰ)治疗甲状腺机能亢进症(甲亢)的近期临床疗效。方法 选择适合~(131)Ⅰ治疗的病例,测定甲状腺吸~(131)Ⅰ率并行甲状腺显像,估算甲状腺的重量。根据经验公式并参考病人的病情、年龄、病程,确定较为确切的治疗量,呆用一次性口服法。治疗后3个月、6个月、12个月复诊。结果 治疗260例甲亢中,225侧痊愈,治愈率86.5％,16例未完全缓解者,其中8例1年后给予第2次~(131)Ⅰ治疗。随访1年时发生甲状腺功能减低(甲低)19例,甲低发生率为7.3％。甲低者口服甲状腺素片替代治疗,维持甲状腺功能正常。结论 ~(131)Ⅰ治疗甲亢是一种安全、有效、复发率低的方法。
Objective To observe the clinical effect of ~ (131) iodine (~ (131) Ⅰ) in the treatment of hyperthyroidism (hyperthyroidism). Methods 131 cases of 131 Ⅰ treatment were selected, and thyroid uptake of 131 Ⅰ was measured in parallel with thyroid imaging to estimate thyroid weight. According to empirical formula and refer to the patient’s condition, age, duration, to determine the more precise treatment, stay with a one-time oral method. 3 months after treatment, 6 months, 12 months referral. Results In the treatment of 260 cases of hyperthyroidism, 225 cases were cured, the cure rate was 86.5%, 16 cases were not completely relieved, of which 8 cases were given the second ~ (131) Ⅰ treatment after one year. 19 cases of hypothyroidism (hypothyroidism) occurred at 1 year follow-up, and the incidence of hypothyroidism was 7.3%. A hypothyroidism oral hypoglycemic substitution therapy to maintain normal thyroid function. Conclusion ~ (131) Ⅰ treatment of hyperthyroidism is a safe, effective, low recurrence rate.