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目的:了解住院网络游戏成瘾(IGD)青少年血清同型半胱氨酸(Hcy)、尿酸(UA)、微量元素水平及以上指标与成瘾的相关性。方法:选取本院收治的60例青少年IGD患者为病例组,同期60例体检健康人员为对照组,将两组血清Hcy、UA及微量元素水平进行检测与统计学比较。应用青少年病理性互联网使用量表(APIUS)对病例组进行评定。结果:病例组血清Hcy、UA、Pb、Fe、Cu水平均高于对照组,Zn水平低于对照组(P值均<0.05)。病例组APIUS项目均分与血清Hcy、UA、Pb水平呈正相关(P<0.01或P<0.05);与Zn水平呈负相关(P<0.05)。结论:血清Hcy、UA、Pb、Zn水平变化可能与网络成瘾密切相关,可作为临床诊断的参考指标。
Objective: To investigate the relationship between serum homocysteine (Hcy), uric acid (UA), trace element levels and the above indexes and addiction in adolescents with online game addiction (IGD). Methods: Sixty cases of adolescent IGD admitted to our hospital were selected as the case group and 60 cases of healthy people as the control group. Hcy, UA and trace element levels were compared between the two groups. The case group was assessed using the Pathology Internet Use Scale for Teenagers (APIUS). Results: The levels of serum Hcy, UA, Pb, Fe and Cu in the case group were higher than those in the control group, while the levels of Zn were lower than those in the control group (all P <0.05). The mean score of APIUS in case group was positively correlated with serum Hcy, UA and Pb levels (P <0.01 or P <0.05), negatively correlated with Zn level (P <0.05). Conclusion: The changes of serum Hcy, UA, Pb and Zn levels may be closely related to internet addiction, which may serve as a reference for clinical diagnosis.