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作者对胃病、癌旁和正常粘膜上皮ＡｇＮＯＲｓ定量与胃癌生物学行为之间的关系，在胃良恶性病变鉴别诊断中的价值以及与ＣＥＡ表达之间的关系作了研究。结果表明，ＡｇＮＯＲｓ量及大小在胃癌、癌旁及正常粘膜中存在极显著差异（Ｐ＜０．０１），其形态和分布在胃良、恶性病变中显著不同，在与ＣＥＡ表达关系分析后发现，两者在反映肿瘤生物学行为及良、恶性病变的诊断方面具相似性。结合两指标可对胃癌的生物学行为及胃良、恶性病变的判断作出较为确切的估计。
The authors studied the relationship between quantification of AgNORs in stomach, adjacent and normal mucosa epithelium and the biological behavior of gastric cancer, the value of differential diagnosis in benign and malignant lesions, and the relationship with CEA expression. The results showed that there was a significant difference in the quantity and size of AgNORs between gastric cancer, paraneoplastic and normal mucosa (P<0.01). The morphology and distribution of AgNORs were significantly different in the gastric and benign lesions. Both have similarities in the diagnosis of tumor biological behavior and the diagnosis of benign and malignant lesions. Combining the two indexes can make a more accurate estimate of the biological behavior of gastric cancer and the judgment of gastric benign and malignant lesions.