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尚有8%~16%甲状腺癌出现复发而最终因癌肿播散而致死,除核素治疗外不少作者探索基因治疗的途径。作者应用分子基因技术在无胸腺裸鼠制作转移性甲状腺癌模型(TGCT),在霍乱毒素A1亚单位经甲状腺球蛋白(TG)基因启动的条件下转染微基因,由TG导向单纯疤疹病毒Ⅰ型胸着激酶
There are 8% to 16% of thyroid cancer recurrence and eventually died of cancer spread. In addition to radionuclide therapy, many authors explore ways of gene therapy. The authors used molecular genetic techniques to generate a metastatic thyroid cancer model (TGCT) in athymic nude mice and to transfect micro genes under the conditions activated by the thyroglobulin (TG) gene in the cholera toxin A1 subunit. TG guided herpes simplex virus Type I thoracic kinase