通过在催化剂的不同位置同时引入LALB(Lewis acid/Lewis base)双功能基团(包括氮氧偶极基团和金属钛中心)来改善其催化活性和立体控制能力,合成基于salen骨架结构的新型氮氧双功能催化剂.在相对温和的条件下成功的将该类双功能催化剂应用于酮的不对称硅氰化反应,表现出了中等程度的选择性和非常高的反应活性. Through the introduction of LALB (Lewis acid / Lewis base) bifunctional groups (including nitrogen and oxygen dipole groups and metal titanium centers) at different positions of the catalyst to improve its catalytic activity and stereocontrol ability, a novel salen-based Nitrogen and oxygen bifunctional catalysts.Under the relatively mild conditions, the successful application of such bifunctional catalysts to the asymmetric silanization of ketones shows moderate selectivity and very high reactivity.