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目的探讨子痫前期并发HELLP综合征的临床特点及相关治疗。方法对75例子痫前期并发HELLP综合征患者在解痉降压治疗的基础上采用激素、输血小板等对症治疗,对其资料进行临床回顾性分析。结果 75例中子痫前期并发HELLP综合征发生于28～37周者65例,发生于37周之后者8例,发生于28周之前者2例。经剖宫产分娩60例(80.00%),经阴道分娩15例(20.00%)。阴道分娩15例中6例行阴道助产,2例引产。全部病例均未出现产后大出血及其他脏器的严重并发症。结论对子痫前期并发HELLP综合征的患者在解痉降压的基础上应用糖皮质激素,输注浓缩血小板可明显提高临床疗效。
Objective To investigate the clinical features and related treatment of preeclampsia complicated with HELLP syndrome. Methods Seventy-five patients with preeclampsia complicated with HELLP syndrome were treated with antispasmodic and antihypertensive drugs, and the data were retrospectively analyzed with symptomatic treatment of hormone and platelet transfusion. Results Seventy-five patients with HELLP syndrome with HELLP syndrome occurred in 28- to 37-week-old in 75 cases, 8 cases occurred after 37 weeks and 2 cases occurred before 28 weeks. Cesarean section delivery of 60 cases (80.00%), vaginal delivery in 15 cases (20.00%). Vaginal delivery in 15 cases 6 cases of vaginal delivery, 2 cases of induced labor. All cases did not appear postpartum hemorrhage and other serious complications of organs. Conclusions Patients with preeclampsia complicated by HELLP syndrome may be treated with glucocorticoid on the basis of antispasmodic and antihypertensive therapy. The infusion of concentrated platelets can significantly improve the clinical efficacy.