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目的对糖尿病合并肾病患者的血液流变学参数变化进行临床观察分析。方法选择我院进行治疗的糖尿病合并肾病患者40例作为治疗组进行研究,另外选择40例健康者作为对照组,使用北京世帝科学仪器公司生产的LG-80血粘度仪对两组患者的血液流变学参数进行检测后做统计学比较比分析。结果经统计学比较可以看出,治疗组患者的血液流变学各项指标均明显高于对照组,差异具有统计学意义(P<0.01～0.05)。结论糖尿病合并肾病患者的血液粘度较正常指标有显著的增高,对糖尿病患者进行定期的血液流变学相关指标检测,不但可以提高对微血管性病变以及肾病的检出率,而且对于疗效观察以及预后有重要的意义。
Objective To analyze the changes of hemorrheological parameters in patients with diabetic nephropathy. Methods Forty patients with diabetic nephropathy who were treated in our hospital were selected as the treatment group. Forty healthy subjects were selected as the control group. Blood samples were collected from two groups of patients using LG-80 blood viscosity meter manufactured by Beijing S & T Scientific Instruments Co., Rheological parameters were tested for statistical comparative analysis. Results By statistical comparison, we can see that all indexes of hemorheology in treatment group were significantly higher than those in control group, the difference was statistically significant (P <0.01 ~ 0.05). Conclusion The blood viscosity of patients with diabetes mellitus and nephropathy is significantly higher than that of the normal ones. The regular hemorheological indexes in diabetic patients can not only improve the detection rate of microvascular disease and nephropathy, but also observe the curative effect and prognosis Is of great significance.