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目的探讨以头颈部为首发部位的恶性淋巴瘤 (ML)的临床特点。方法回顾性分析 5 2例患者的临床资料。结果首发部位 :颈部2 4例 ,口腔颌面部 8例 ,鼻部 7例 ,咽部 13例。发生于淋巴结者 2 4例 ,淋巴结外组织者 2 8例。可明确恶性程度的 40例中高度恶性占61.5 % ;中度恶性占 13 .5 %。治疗以放疗和化疗为主 ,6例局限性 ML均采用手术治疗 ;5 2例中死亡 13例 ,无瘤生存 19例 ,复发 5例 ,失访 15例。结论头颈部 ML恶性程度高 ,表现形式多样 ,注意鉴别诊断。治疗以放疗和化疗为主 ,局限性 ML应先争取手术治疗
Objective To investigate the clinical features of malignant lymphoma (ML) with the head and neck as the first site. Methods The clinical data of 52 patients were retrospectively analyzed. The results of the first place: neck 24 cases, 8 cases of oral and maxillofacial, nasal 7 cases, 13 cases of pharynx. Twenty-four cases occurred in lymph nodes and 28 cases occurred in lymph node tissues. Of the 40 patients with moderate malignancy, 65% were moderately malignant and 13.5% were moderately malignant. The treatment was mainly radiotherapy and chemotherapy. Six cases of localized ML were treated with surgery; 13 cases died in 52 cases, 19 cases survived without tumor, 5 cases relapsed, and 15 cases lost follow-up. Conclusions The malignancy of head and neck ML is high and its manifestations are various. Attention should be paid to differential diagnosis. The treatment is mainly based on radiotherapy and chemotherapy. The limitations of ML should be first for surgical treatment.