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测定１２例男性脑梗塞患者入院第２天、８天和第１５～３０天血清雌二醇（Ｅ２）、睾酮（Ｔ）及Ｅ２／Ｔ比值，以健康人为对照组，动态观察性激素的变化规律。结果：（１）脑梗塞组入院后第２天、８天、１５～３０天Ｅ２、Ｔ和Ｅ２／Ｔ比值差异无显著性（Ｐ＞０．０５）；（２）脑梗塞组入院后第２天、８天、１５～３０天Ｅ２、Ｔ和Ｅ２／Ｔ比值较对照组明显增高（Ｐ＜０．０１），入院第２天Ｔ水平与健康对照组差异无显著性（Ｐ＞０．０５），第８天，１５～３０天时差异有显著性（Ｐ＜０．０５）。提示血清Ｅ２增高参与了脑梗塞形成过程，Ｅ２／Ｔ比值增高可能是男性脑梗塞患者的易患因素
Serum estradiol (E2), testosterone (T) and E2 / T ratio were measured at 12 days, 8 days and 15-30 days after admission in 12 male patients with cerebral infarction. The changes of sex hormones were observed dynamically in healthy volunteers . Results: (1) There were no significant differences in E2, T and E2 / T ratios between the two groups on day 2, day 8 and day 15 to 30 after admission (P> 0.05). (2) The ratios of E2, T and E2 / T at 2 days, 8 days and 15-30 days were significantly higher than those in the control group (P <0.01). There was no significant difference in T level between the second day and the healthy control group (P> 0.05). 05). On the 8th and 15th to 30th days, the difference was significant (P <0.05). Suggesting that elevated serum E2 is involved in the process of cerebral infarction. The increase of E2 / T ratio may be a predisposing factor for male patients with cerebral infarction