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目的了解西藏拉萨市世居藏族农村居民慢性肝胆疾病患病现状及其危险因素,为采取相应的干预措施提供参考依据。方法采用分层随机抽样方法在拉萨市墨竹工卡县和林周县抽取的1 737名年龄≥18岁世居藏族农村居民进行问卷调查、体格检查、肝胆疾病B超检查和肝功能检测。结果拉萨地区世居藏族农村居民慢性肝胆疾病总患病率为22.3%,各类型肝胆疾病患病率由高到低依次为:胆囊炎(11.3%)、胆囊结石(6.2%)、脂肪肝(4.5%)、肝包虫病(1.9%)、肝血管瘤(1.6%)、肝硬化(0.8%);多因素非条件logistic回归分析结果显示,女性、年龄≥45岁、月平均收入>2 000元、超重、肥胖、中心性肥胖和谷丙转氨酶(ALT)升高是拉萨地区世居藏族农村居民慢性肝胆疾病患病的危险因素。结论拉萨地区世居藏族农村居民慢性肝胆疾病以胆囊炎为主,女性、年龄较大、月平均收入较高、体质指数(BMI)和ALT较高以及中心性肥胖居民是该地区慢性肝胆疾病防治的重点人群。
Objective To understand the prevalence and risk factors of chronic hepatobiliary diseases among rural residents in Lhasa, Tibet, and to provide a reference for the corresponding interventions. Methods A stratified random sampling method was used to survey 1 737 rural residents aged 18 or older who lived in villages of Moqon County and Linzhou County in Lhasa City. Physical examination, hepatobiliary disease B-ultrasound and liver function tests were conducted. Results The total prevalence of chronic hepatobiliary diseases in resident Tibetan rural residents in Lhasa was 22.3%. The prevalence of various types of hepatobiliary diseases was cholecystitis (11.3%), gallstone (6.2%), fatty liver 4.5%), hepatic echinococcosis (1.9%), hepatic hemangioma (1.6%) and cirrhosis (0.8%). Multivariate non-conditional logistic regression analysis showed that female, age≥45 years, average monthly income> 2 000 yuan, overweight, obesity, central obesity and elevated alanine aminotransferase (ALT) is a risk factor for chronic liver and gallbladder disease in rural residents living in Lhasa. Conclusion Chronic liver and gallbladder diseases are predominantly cholecystitis in rural residents of Lhasa, with older women, higher average monthly income, higher body mass index (BMI), higher ALT and central obesity among residents with chronic hepatobiliary diseases in the area The focus of the crowd.