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目的:分析2008-2014年南方医院孕妇HBV感染情况。方法:回顾性分析这7年间于南方医院分娩的22 906例孕妇的资料。结果:孕妇的HBs Ag阳性率为9.45%,其中,广东籍、非广东籍的分别为11.64%、6.16%(χ2=193.370,P<0.005)。每年孕妇的HBs Ag阳性率分别为12.24%、12.98%、10.80%、9.36%、8.20%、8.03%、8.27%。HBe Ag阳性、HBe Ag阴性孕妇的ALT异常率分别为17.96%、6.68%(χ2=62.594,P<0.005);1992年前、后出生孕妇的HBs Ag阳性率分别为9.55%、6.64%(χ2=6.578,P=0.01)。结论:广东籍孕妇的HBV携带率高于非广东籍;孕妇HBs Ag阳性率呈逐年下降趋势;HBe Ag阳性孕妇中ALT异常率高于HBe Ag阴性孕妇;1992年后出生的孕妇,其HBV携带率明显下降。
Objective: To analyze HBV infection in pregnant women in Nanfang Hospital from 2008 to 2014. Methods: The data of 22 906 pregnant women who gave birth in Nanfang Hospital during the past seven years were retrospectively analyzed. Results: The positive rate of HBs Ag in pregnant women was 9.45%. Among them, Guangdong and non-Guangdong were 11.64% and 6.16% respectively (χ2 = 193.370, P <0.005). The positive rates of HBs Ag in pregnant women were 12.24%, 12.98%, 10.80%, 9.36%, 8.20%, 8.03% and 8.27% respectively. The positive rates of HBsAg in HBeAg-positive and HBeAg-negative pregnant women were 17.96% and 6.68%, respectively (χ2 = 62.594, P <0.005). The positive rates of HBsAg in pregnant women before and after 1992 were 9.55% and 6.64% = 6.578, P = 0.01). Conclusion: The prevalence of HBsAg in Guangdong pregnant women shows a trend of decreasing year by year. The abnormal rate of ALT in HBeAg-positive pregnant women is higher than that of HBeAg-negative pregnant women. The pregnant women born after 1992 have HBV carriers The rate dropped significantly.