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采用自制的离心雾化设备制备了肠溶吲哚美辛微囊。对设备的性能和微囊的性质进行了考察，当雾化转速３５００～５５００ｒ·ｍｉｎ－１，供液速度５０ｍｌ·ｍｉｎ－１时，制得粒径１５０～３５０μｍ，产率＞７０％的微囊。微囊溶出速率与母液和接收器内囊材的性质有关。此方法简单，易操作，影响因素少。
Indomethacin microcapsules were prepared by self-made centrifugal atomization equipment. The performance of the equipment and the properties of the microcapsules were investigated. When the atomization speed was 3500-5500 r · min-1 and the feeding speed was 50 ml · min-1, the micro-capsules with the diameter of 150-350 μm and the yield of> 70% bag. The microcapsule dissolution rate is related to the nature of the mother liquor and the inner capsule material of the receiver. This method is simple, easy to operate, less influencing factors.