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目的:探讨早发型重度子痫前期结束妊娠的孕周与妊娠结局之间的关系。方法:回顾分析长春市妇产医院治疗的早发型重度子痫前期患者146例,将妊娠30～34周结束妊娠重度子痫前期的患者按结束妊娠的时间分为两组,孕30～32周结束妊娠67例为A组,孕32～34周结束妊娠79例为B组。结束妊娠前均进行期待治疗,最少24 h,最多7天,均给予地塞米松5 mg,每天2次肌注,共2天。主要观察两组与围生儿的病死率、Apgar评分以及与孕母发生胎盘早剥、子痫、累及脏器、HELLP综合征等之间的关系。结果:A组与B组围生儿病死率及Apgar评分差异有统计学意义(P<0.05);A组与B组孕母并发症差异无统计学意义(P>0.05)。结论:结束妊娠时间越早围生儿死亡率越高、Apgar评分越低,而在一定限期的期待治疗中孕母并发症的发生无明显增加。故早发型重度子痫前期患者根据患者的具体情况应该尽量进行期待治疗。
Objective: To investigate the relationship between gestational age and pregnancy outcome in early-onset severe preeclampsia. Methods: A retrospective analysis of 146 cases of early-onset severe preeclampsia patients treated in Changchun Maternity Hospital. The patients with severe pre-eclampsia who finished gestation 30-34 weeks of gestation were divided into two groups according to the time of termination of gestation, and the gestational age ranged from 30 to 32 weeks End of pregnancy in 67 cases for the A group, the end of pregnancy 32 to 34 weeks 79 cases of group B. Expected to be treated before the end of pregnancy, a minimum of 24 h, up to 7 days, were given dexamethasone 5 mg, 2 times a day intramuscular injection, a total of 2 days. Mainly observe the two groups and perinatal mortality, Apgar score and pregnant women with placental abruption, eclampsia, involving organs, HELLP syndrome, the relationship between. Results: There was a significant difference in perinatal mortality and Apgar scores between groups A and B (P <0.05). There was no significant difference in gestational age between group A and group B (P> 0.05). Conclusion: The higher the rate of perinatal mortality, the lower the Apgar score, and no significant increase in the incidence of maternal complications in a certain period of expectant treatment. Therefore, patients with early-onset severe preeclampsia should be treated according to the specific circumstances of patients as expected.