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目的:探讨透析充分性及其他躯体因素、社会经济因素对维持性血液透析(简称血透)患者抑郁症发生的影响,并在此基础上为提高临床血透的整体疗效提供科学依据。方法:采用ZungSDS抑郁自评表对51例终末期肾病(ESRD)患者进行评估,并分析透析充分性及躯体因素、社会经济因素对ESRD患者抑郁症的影响。结果:51例维持性血透ESRD患者Zung抑郁自评量表抑郁严重指数大于0.5者32例,占63%;透析不充分组患者抑郁症发生率(24例,77%)较透析充分组(8例,40%)显著升高(P<0.01);2年随访期内死亡患者透析不充分组比透析充分组明显增多(P<0.05),两组疲劳、失眠、头疼、血管痛、不安腿综合征及经济状况差异均存在显著性(P<0.01,P<0.05);其中,疲劳、失眠、头疼、血管痛及经济状况的恶化、离异、朋友及家庭支持的减少与抑郁症的发生相关。结论:透析不充分、躯体因素及社会经济因素对维持性血透患者抑郁症的发生均有影响。
Objective: To study the effect of dialysis adequacy, other physical factors and socioeconomic factors on the occurrence of depression in maintenance hemodialysis patients, and to provide a scientific basis for improving the overall efficacy of hemodialysis on this basis. Methods: Fifty-one patients with end-stage renal disease (ESRD) were evaluated using the ZungSDS Depression Rating Scale. The effects of dialysis adequacy and somatic and socioeconomic factors on depression were evaluated. Results: 51 patients with maintenance hemodialysis ESRD patients with Zung depression self-rating scale severe depression index greater than 0.5 in 32 cases, accounting for 63%; dialysis inadequate group of patients with depression (24 cases, 77%) than dialysis adequate group 8 cases, 40%) were significantly higher (P <0.01). In the 2-year follow-up period, the number of deaths in patients with inadequate dialysis was significantly higher than that in the dialysis adequate group (P <0.05). The fatigue, insomnia, headache, (P <0.01, P <0.05). Among them, fatigue, insomnia, headache, vomitus and economic deterioration, divorce, reduction of friends and family support, and the occurrence of depression Related. Conclusion: Inadequate dialysis, physical factors and socio-economic factors have an impact on the occurrence of depression in maintenance hemodialysis patients.