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系统性红斑狼疮(systemic lupus erythematosus,SLE)等自身免疫系统疾病以产生大量针对核抗原的自身抗体为显著特点,干扰素(interferons,IFNs)与SLE的活动性及严重程度相关。Toll样受体(toll-like receptors,TLRs)为模式识别受体(patternrecognition receptors,PRRs)[1]中的信
Systemic lupus erythematosus (SLE) and other autoimmune diseases are characterized by a large number of autoantibodies against nuclear antigens. Interferons (IFNs) are associated with the activity and severity of SLE. Toll-like receptors (TLRs) are signals in pattern recognition receptors (PRRs) [1]