恶性外耳道炎由绿脓杆菌引起,可侵犯颅底的骨结构及颅神经,甚至引起死亡,作者于87至88年间,对23例该患者给予口服丙氟哌酸1.5～2.25g/day,6周。与此同时,一般在全麻下,清创外耳道。结果,21例治愈,随访9～25个月无复发。只有2例治疗失败。除2例有头痛、烦燥、眩晕外,无其它副作用发现。故认为口服丙氟哌酸与以往倡用的静脉用药的 Malignant otitis externa is caused by Pseudomonas aeruginosa, which can invade the skull base’s cranial nerves and cranial nerves, and even cause death. From 23 to 87 patients, 23 patients were given oral oral propanicic acid 1.5-2.25g / day, 6 week. At the same time, generally under general anesthesia, debridement of the external auditory canal. Results, 21 cases were cured, followed up for 9 to 25 months without recurrence. Only 2 cases failed treatment. In addition to 2 cases of headache, irritability, dizziness, no other side effects found. Therefore, oral administration of propofol and intravenous prophylaxis in the past