脑组织立体定向活检是一种准确定位脑组织内部病变的有效检查方法,适应于下列情况:1)患者年龄较大/或太虚弱而不能耐受开颅术者,2)病变部位深、广泛,位于优势半球,功能性脑皮质区或混合区,3)病变范围很小,不宜手术治疗者。由于立体定向活检通常使用局部麻醉,只需在颅骨上开一小孔,对神经外科医生,内科医生乃至病人来说容易低估其可能出现的并发症。然而这种操作过程是“看不见”的,并常用于深部脑中线区病变,因此操作者应估计到严重并发症,尤其是与出血有关的并发症的发生。 资料与方法:从1986年4月至1993年6月作者对300例患者实施了脑组织活检术。患者年龄在18—88岁,平均54岁,2例儿童年龄为2岁和6 Stereotactic biopsy of brain tissue is an effective method to accurately locate the internal lesion in brain tissue, and is suitable for the following cases: 1) patients who are older or too weak to tolerate craniotomy, 2) deep and extensive lesions , Located in the dominant hemisphere, functional cortical area or mixed area, 3) the lesion is very small, not surgical treatment. Because stereotactic biopsy usually uses local anesthesia, only a small hole in the skull, neurosurgeons, physicians and even patients is easy to underestimate the possible complications. However, this procedure is “invisible” and is commonly used for deep brain midline lesions, so operators should assess serious complications, especially bleeding-related complications. Materials and Methods: From April 1986 to June 1993, the authors performed brain biopsy in 300 patients. Patients ranged in age from 18 to 88 years with an average of 54 years and 2 children were 2 and 6 years old