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艾滋病(AIDS)是一种由艾滋病病毒(HIV)感染引起的世界性传染病,HIV携带者一旦发病,其死亡率可达100%。近年来由于AIDS在世界范围内广泛传播,我国也发现有AIDS患者和HIV携带者,且数量呈增长的趋势。对AIDS的治疗目前尚无理想药物,国际公认并已批准生产的抗HIV药物,只有叠氮脱氧胸苷(AZT)、双脱氧肌苷(DDI)、双脱氧胞苷(DDC)等几种核苷类合成药。这些药物只能抑制HIV致细胞病变,或暂时抑制HIV复制延缓发病,而不能彻底清除HIV及避免患者最终死亡。上述药物因毒副作用很大并易产生耐药性,且价格昂贵,影响了这些药物
AIDS is a worldwide infectious disease caused by the AIDS virus (HIV). Mortality rates of HIV carriers up to 100% once they occur. In recent years, AIDS is widely spread all over the world, and AIDS patients and HIV carriers are also found in our country, and the quantity shows a tendency of increase. AIDS treatment is currently no ideal drug, the internationally recognized and approved the production of anti-HIV drugs, only azidothymidine (AZT), dideoxyinosine (DDI), dideoxycytidine (DDC) and several other nuclear Glycosides synthetic drugs. These drugs can only inhibit HIV cytopathic effect, or temporarily inhibit HIV replication delay the onset, but not completely eliminate HIV and prevent the patient eventually died. These drugs because of the side effects and easy to produce drug resistance, and expensive, affecting these drugs