论文部分内容阅读
我们应用三维结构（３－Ｄ）再构成计算机系统，以０．２ｍｍ间隔连续切片，ＨＥ染色，对５０例经纤维结肠镜切除的大肠腺瘤各种异型上皮的体积及分布规律进行研究。其中癌变１７例（３４％），其平均体积是单纯腺瘤的３．４倍。腺瘤体积越大，其癌变率越高，但体积较小的亚有蒂型腺瘤也有很高癌变率（２５％）。研究结果表明腺瘤体积大小与平均异型度无相关关系。用常规方法切片，仅检出１４例有癌变，漏诊率１８％。为提高腺瘤癌变检出率，至少应以０．６ｍｍ间隔连续切片。此种方法对准确判定断端有无癌浸润也有重要意义。
We used a three-dimensional structure (3-D) to reconstruct the computer system. The sections were serially sectioned at 0.2mm intervals and stained with HE. The volume and distribution of various heterotypic epithelia in 50 cases of colon adenomas removed by colonoscopy were studied. Among them, 17 cases (34%) were cancerous and the average volume was 3.4 times that of simple adenomas. The larger the volume of adenoma, the higher the cancer rate, but the smaller size of sub-adrenal adenoma also has a high rate of cancer (25%). The results of the study showed that there was no correlation between the size of adenomas and the mean isoformity. Only 14 cases with cancer were detected by routine methods. The rate of missed diagnosis was 18%. In order to increase the detection rate of adenoma canceration, at least 0.6mm intervals should be consecutively sliced. This method is also important for accurately determining whether there is cancer infiltration at the stump.