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本文总结1973~1984年间,138例小儿肾病综合征的临床及随访结果,男性多于女性(3∶1),单纯型以3~6岁为多,肾炎型发病高峰分别为3~7岁和10~14岁。单纯型89例,肾炎型49例,初发病9例,复治或转诊129例。随访84例中从未复发的痊愈者23例(27.49%),曾有复发但已基本痊愈40例(47.6%),多次复发及未缓解12例(14.3%),死亡9例(10.7%)。治疗单用激素效果差易复发,本组服药三月内均复发,从未复发23例,均服药6月以上。体会大剂量激素中长疗程为好,短疗程易复发,6~9月为宜,肾炎型一年以上,同时加环磷酰胺。五组治疗均以单纯性优于肾炎性。
This article summarizes the clinical and follow-up results of 138 children with nephrotic syndrome from 1973 to 1984, more men than women (3: 1), simple type of 3 to 6 years old, nephritis onset peak were 3 to 7 years and 10 ~ 14 years old. 89 cases of simple type, 49 cases of nephritis, initial 9 cases, retreatment or referral 129 cases. There were 23 cases (27.49%) who had never relapsed in 84 cases, 40 cases (47.6%) had recurrence but basically recovered, 12 cases (14.3%) had multiple recurrence and no remission, 9 cases (10.7% ). Treatment with single hormone effect is easy to relapse, this group were relapsed within three months, never relapsed in 23 cases, were taking more than 6 months. Experience long-term treatment of large doses of hormone as well, a short course of relapse, 6 to 9 months is appropriate, more than one year of nephritis, plus cyclophosphamide. Five groups of treatment are simple than nephritis.