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目的观察依达拉奉对急性脑出血的治疗效果。方法将63例脑出血患者随机分为研究组和对照组,研究组在常规治疗的基础上,给予依达拉奉30mg加生理盐水100ml静脉滴注,30min内滴完,2次/d,2周为1个疗程。分别于治疗前及治疗后2、4周进行神经功能缺损程度(NIHSS)及日常生活活动量(ADL)评分,并进行统计学分析。结果研究组与对照组在治疗2、4周的NDS及ADL评分差异均有统计学意义(P<0.05),研究组用药前后相比NIHSS及ADL评分差异有高度统计学意义(P<0.05),对照组治疗2、4周后相比NIHSS评分差异无统计学意义(P>0.05),而ADL评分有高度统计学意义(P<0.01)。结论依达拉奉可明显促进脑出血患者的神经功能康复。
Objective To observe the therapeutic effect of edaravone on acute cerebral hemorrhage. Methods Sixty-three patients with intracerebral hemorrhage were randomly divided into study group and control group. On the basis of routine treatment, the study group was given edaravone 30mg plus 100ml normal saline intravenously, drip finished 30min, twice a day, 2 Week for a course of treatment. The degree of neurological deficit (NIHSS) and daily living activity (ADL) were measured before treatment and 2, 4 weeks after treatment, respectively, and statistical analysis was performed. Results There were significant differences in NDS and ADL score between study group and control group at 2 and 4 weeks (P <0.05). There was a statistically significant difference between NIHSS and ADL scores before and after treatment in study group (P <0.05) There was no significant difference between the two groups in the NIHSS score after treatment for 2 and 4 weeks (P> 0.05), while the ADL score was highly significant (P <0.01). Conclusion Edaravone can obviously promote the neurological rehabilitation of patients with cerebral hemorrhage.