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目的:观察米索前列醇片在晚期妊娠合并子宫肌瘤者剖宫产中行子宫肌瘤剔除术的应用效果。方法:选取2004年12月～2008年12月本院治疗的32例晚期妊娠合并子宫肌瘤的患者,在剖宫产术中待胎儿及其附属物娩出后舌下含服0.6 mg米索前列醇片后再行子宫肌瘤剔除术,以43例剖宫产中行子宫肌瘤剔除术未应用米索前列醇片者进行对照,比较两组住院时间、手术后血红蛋白值、手术时间、术中出血量、手术前后血红蛋白值差值等。结果:32例晚期妊娠合并子宫肌瘤患者在剖宫产同时应用米索前列醇片后行子宫肌瘤剔除术,手术时间、产后出血、输血及产后感染率发生率均没有显著增加,差异无统计学意义(P>0.05)。但是手术失血量明显减少,观察组为(332.44±31.43)ml,对照组为(391.47±18.27)ml,差异有统计学意义(P<0.05)。结论:剖宫产同时行子宫肌瘤剔除术应用米索前列醇片可明显减少术中出血量,减少了产后出血的发生及输血的几率,且不良反应少,临床应用方便,适合推广。
Objective: To observe the effect of misoprostol tablets in the treatment of uterine myomectomy in cesarean section in late pregnancy with uterine fibroids. Methods: Thirty-two patients with advanced uterine fibroids treated in our hospital from December 2004 to December 2008 were enrolled in this study. The fetuses and their appendages were subconjunctivally implanted 0.6 mg misoprostol in cesarean section Alcohol tablets and then myomectomy, with cesarean section in 43 cases of myomectomy without misoprostol tablets were compared, length of stay in hospital, postoperative hemoglobin value, operation time, intraoperative Bleeding, hemoglobin value before and after surgery, and so on. Results: 32 cases of patients with uterine fibroids in the second trimester of pregnancy were treated with misoprostol and cesarean still after myomectomy. There was no significant difference in operative time, postpartum hemorrhage, blood transfusion and postpartum infection rates between the two groups Statistical significance (P> 0.05). However, the amount of blood loss decreased significantly in the observation group (332.44 ± 31.43) ml and in the control group (391.47 ± 18.27) ml, the difference was statistically significant (P <0.05). Conclusion: Cesarean section at the same time the myomectomy curative effect of misoprostol tablets can significantly reduce the amount of intraoperative bleeding, reduce the incidence of postpartum hemorrhage and blood transfusion, and less adverse reactions, clinical application, suitable for promotion.