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目的分析国人动脉中心收缩压分数(FSP)和舒张压分数(FDP)与动脉粥样硬化性肾动脉狭窄的相关性。方法应用Lead 2000多导生理记录仪描记入选研究对象中心压力曲线,并计算中心FSP和FDP;以肾动脉造影结果作为分组依据,分为肾动脉狭窄组71例和非肾动脉狭窄组489例,分析中心动脉血压分数FSP、FDP与肾动脉狭窄的关系。结果肾动脉狭窄组的中心FSP显著高于非肾动脉狭窄组[分别为1.50±0.14vs1.39±0.11],而中心FDP显著低于非肾动脉狭窄组[分别为0.75±0.071vs0.80±0.058],(均P<0.01)。Logistic回归分析结果示:中心的而非外周的FSP和FDP为影响肾动脉狭窄的独立危险因素(OR=1.092,95%CI=1.03~1.28 for FSP;OR=0.87,95%CI=0.37~0.94 for FDP)。结论中心动脉FSP、FDP为预测肾动脉狭窄提供了重要参考价值
Objective To analyze the relationship between systolic blood pressure (FSP) and diastolic blood pressure (FDP) and atherosclerotic renal artery stenosis in Chinese people. Methods The center pressure curves of the study subjects were recorded by Lead 2000 multi-channel physiology recorder and the central FSP and FDP were calculated. According to the results of renal artery angiography, 71 patients were divided into renal artery stenosis group and 489 non-renal artery stenosis group, Analysis of the relationship between arterial blood pressure score FSP, FDP and renal artery stenosis. Results The central FSP of patients with renal artery stenosis was significantly higher than that of non-renal artery stenosis [1.50 ± 0.14 vs 1.39 ± 0.11], while the central FDP was significantly lower than that of non-renal artery stenosis [0.75 ± 0.071 vs 0.80 ± 0.058] (all P <0.01). Logistic regression analysis showed that central and not peripheral FSP and FDP were independent risk factors for renal artery stenosis (OR = 1.092, 95% CI = 1.03-1.28 for FSP; OR = 0.87, 95% CI = 0.37-0.94 for FDP). Conclusion The central artery FSP, FDP for the prediction of renal artery stenosis provides an important reference value