临床上在输精管结扎术中常使用醋酸苯汞或硝酸苯汞溶液注入向精囊一端,来杀死残留的精子,以取消手术后的避孕期(否則手术后三月内仍需避孕)。唯醋(硝)酸苯汞有时不易購买,我們在寻求代用品方面进行了一些研究。从尼泊金(Nipagin)的性質和作用看来,是醋(硝)酸苯汞的良好代用品。尼泊金是对-羟基苯甲酸甲酯(Nipagin M)与对-羟基苯甲酸乙酯(Nipagin A)的等量混合物,是一种强有力的防霉消毒剂。它的性質稳定,受PH变化的影响不大(本刊6卷317页),能溶于多种有机溶剂而不起变化,高压消毒不致破坏,且因本身是抑霉菌剂,能保存较長时間,可 Clinically, in the vasectomy process, phenylmercuric acetate or phenylmercuric nitrate is often used to inject into the seminal vesicle to kill the remaining sperm to eliminate the postoperative contraceptive period (otherwise, contraception is still required within 3 months after surgery). Phenyl mercury alone is sometimes not readily available, and we have conducted some research in search of alternatives. Judging from the nature and role of Nipagin, it is a good substitute for phenyl mercury vinegar. Paraben is an equal mixture of methyl p-hydroxybenzoate (Nipagin M) and ethyl p-hydroxybenzoate (Nipagin A) and is a powerful anti-mold disinfectant. It is stable in nature and is not affected by the change in pH (Journal of Volume 6, page 317). It dissolves in many organic solvents and does not change. It is not destroyed by autoclaving, and because it is an antifungal agent, it can be stored for a long time. Time, can