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目的探讨鼻咽癌(nasopharyngeal Carcinoma,NPC)放疗后鼻部并发症的临床特点及诊治方法。方法对NPC放疗后鼻出血(nosebleed,NB)患者1例,NB并鼻窦炎(sinusitis)1例进行诊治,并回顾性分析该2例患者的病因及治疗方法。结果患者一号在多次填塞止血无效后采用鼻内镜(Nasal endoscopy,NE)下电凝止血,疗效显著,且随访1年未复发。患者二号采取NE下激光止血,并使用抗生素联合鼻腔冲洗治疗鼻窦炎,疗效显著,随访至今未复发。结论 NE下应用激光以及电凝法止血能有效治疗NPC放疗后并发NB,抗生素联合鼻腔冲洗治疗鼻窦炎,疗效显著,值得推广。
Objective To investigate the clinical features, diagnosis and treatment of nasal complications after radiotherapy of nasopharyngeal carcinoma (NPC). Methods One case of nosebleed (NB), one case of NB and sinusitis were treated by NPC after radiotherapy. The etiology and treatment of the two patients were retrospectively analyzed. Results Patient No. 1 received hemostasis by nasal endoscopy (NE) after multiple tamponade hemostasis was ineffective, and did not recur for one year after follow-up. Patient No. 2 took NE laser to stop bleeding, and used antibiotics combined with nasal irrigation to treat sinusitis. The curative effect was significant and no recurrence was observed up to now. Conclusion NE and laser coagulation and hemostasis can effectively treat NPC after radiotherapy combined with NB, antibiotics combined with nasal irrigation for the treatment of sinusitis, the effect is significant and worth promoting.