治疗严重感染常规需要连续静脉用抗生素7天以上,而口服环丙氟哌酸(ciprofloxacin)具有与静脉用抗生素效力相当的药效学和抗菌特性。本研究旨在确定严重感染时能否缩短静脉抗生素用药疗程而代之以口服环丙氟哌酸。病人和方法自1987年9月至1989年3月期间,选105例患严重感染预计需要8天以上静脉滴注抗生素治疗的成年病人列入观察。 Serious infections often require continuous intravenous antibiotics for more than 7 days, whereas oral ciprofloxacin has comparable pharmacodynamic and antibacterial properties to intravenous antibiotics. The aim of this study was to determine if short courses of intravenous antibiotics could be shortened and oral ciprofloxacin instead. Patients and Methods Between September 1987 and March 1989, 105 adult patients with severe infections expected to require intravenous antibiotics over 8 days were included in the study.