聚烯吡酮碘(Povidine Iodine)是高效局部消毒剂,但用于烧伤创面可能造成肾衰、代谢性酸中毒,高钠血症,又引起渗透性过高等併发症。也有人报道先天性脐疝或腹壁切口感染的婴儿使用聚烯吡酮碘之后,发生一过性甲状腺功能低下。婴儿肠造瘘再吻合,用10%聚烯吡酮碘溶液灌洗既可减少局部细菌污染,也能防止菌血症和吻合口裂开,不过至今为止,给新生儿用聚烯吡酮碘准备肠道,尚无有关吸收游离碘的报道。用大鼠口服此药的急性毒性试验证明,碘的平均致死量为800 mg/kg。作者报道4例新生儿2例因坏死性小肠结肠炎(NEC)併发小肠穿孔,行肠切除回肠造瘘术,1例原因不明的小肠穿孔。行剖腹探查和回肠造瘘术。第4 Povidine Iodine is a highly effective topical disinfectant, but burn wounds can cause kidney failure, metabolic acidosis, hypernatremia and complications such as hyperpermeability. It has also been reported that congenital umbilical or abdominal incision infection in infants after using povidone iodine, a transient hypothyroidism. Infant intestinal fistula and then anastomosis, with 10% povidone iodine solution lavage can reduce local bacterial contamination, but also to prevent bacteremia and anastomotic dehiscence, but so far, to the newborn with povidone iodine Preparation of intestinal, there is no report about the absorption of free iodine. Acute toxicity test with oral administration of this medicine in rats demonstrated that the average lethal dose of iodine was 800 mg / kg. The authors report 2 cases of 4 neonates due to necrotizing enterocolitis (NEC) complicated by intestinal perforation, bowel resection ileostomy, an unexplained intestinal perforation. Laparotomy and ileostomy. Fourth