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目的:评价高龄急性冠脉综合征(acute coronary syndrome,ACS)患者行经皮冠状动脉介入(percutaneous coronary intervention,PCI)治疗的安全性和有效性。方法:对比分析108例高龄ACS患者(≥75岁组)和176例非高龄ACS患者(<75岁组)冠状动脉造影特征、PCI治疗的情况,即刻手术成功率、住院及随访期间主要心血管事件的发生情况。结果:高龄组与非高龄组比较,冠状动脉病变多为多支病变(72.2%比31.8%,P<001);2组手术即刻成功率无明显差异;2组术后达到心肌梗塞溶栓(thrombolysis in myo-cardial infarction,TIMI)3级血流患者比率无明显差异;高龄组手术操作时间非高龄组长[(68.4±25.4)min比(53.7±21.8)min,P<0.05];高龄组住院期间、随访期间累计总的主要心血管事件发生率明显高于非高龄组。结论:对高龄ACS患者行PCI治疗是比较安全而有效的再灌注手段。
Objective: To evaluate the safety and efficacy of percutaneous coronary intervention (PCI) in elderly patients with acute coronary syndrome (ACS). Methods: Coronary angiography was performed in 108 elderly ACS patients (≥75 years old) and 176 non-elderly ACS patients (≤75 years old). The PCI, the immediate success rate of surgery, the major cardiovascular events during hospitalization and follow-up The occurrence of the incident. Results: Compared with non-elderly group, coronary artery lesions were mostly multi-vessel lesions (72.2% vs 31.8%, P <001). There was no significant difference in success rate between the two groups immediately after operation. Thrombolysis in myocardial infarction (68.4 ± 25.4) min vs (53.7 ± 21.8) min, P <0.05]. In the advanced age group, there was no significant difference in grade 3 blood flow between the two groups During hospitalization, the cumulative total major cardiovascular events during follow-up were significantly higher than those in non-senior subjects. Conclusion: PCI is a safe and effective method of reperfusion in elderly patients with ACS.