嗜酸细胞增多综合征(HES)是以末梢血嗜酸细胞增多和多器官嗜酸细胞浸润为特征的一种性质不明的疾病。心功能不全与高发病率和死亡率有关。本病主要见于中年人;迄今为止,15岁以下儿童经尸检证实为HES的仅12例。本文描述了一例有明显末梢血嗜酸细胞增多、白血病前状态、充血性心力衰竭的9岁男孩的临床表现和尸检所见。 Eosinophilia syndrome (HES) is an unidentified disease characterized by peripheral blood eosinophilia and multiple organ eosinophil infiltration. Cardiac insufficiency is associated with high morbidity and mortality. The disease is mainly seen in middle-aged people; so far, children under 15 years of age confirmed by autopsy as only 12 cases of HES. This article describes the clinical presentation and autopsy findings of a 9-year-old boy with significant peripheral eosinophilia, pre-leukemia, and congestive heart failure.