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目的:观察坎地沙坦酯联合苯磺酸氨氯地平治疗原发性高血压的临床效果。方法:将我院2009年7月—2010年6月就诊的152例原发性高血压患者随机分为三组,A组50例采用坎地沙坦酯治疗,B组50例采用苯磺酸氨氯地平治疗,C组52例采用坎地沙坦酯联合苯磺酸氨氯地平治疗,比较三组的临床治疗情况。结果:C组的总有效率为98.1%,明显高于A、B组的84.0%、82.0%,差异均有统计学意义(P<0.05);治疗过程中三组均无严重不良反应发生。结论:坎地沙坦酯联合苯磺酸氨氯地平治疗原发性高血压临床疗效满意,且无严重不良反应发生,值得临床推广应用。
Objective: To observe the clinical effect of candesartan cilexetil and amlodipine besylate in the treatment of essential hypertension. Methods: A total of 152 patients with essential hypertension treated in our hospital from July 2009 to June 2010 were randomly divided into three groups. Group A (50 cases) was treated with candesartan cilexetil, and group B (50 cases) Amlodipine treatment, C group of 52 patients with candesartan cilexetil and amlodipine besylate treatment, the clinical treatment of three groups were compared. Results: The total effective rate in group C was 98.1%, which was significantly higher than 84.0% and 82.0% in group A and B, respectively (all P <0.05). No adverse reactions occurred in the three groups during the treatment. CONCLUSION: Candesartan cilexetil and amlodipine besylate are effective in treating essential hypertension with no serious adverse reactions, which is worthy of clinical application.